Feeding a high-concentrate corn straw diet increased the release of endotoxin in the rumen and pro-inflammatory cytokines in the mammary gland of dairy cows

饲喂高浓度玉米秸秆日粮可增加奶牛瘤胃内毒素的释放和乳腺促炎细胞因子的释放

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作者:Jun Zhou, Guozhong Dong, Changjin Ao, Sen Zhang, Min Qiu, Xi Wang, Yongxia Wu, Khas Erdene, Lu Jin, Chunlong Lei, Zhu Zhang

Background

The

Conclusions

Results indicated that the high-concentrate corn straw diet increased the concentrations of endotoxin in rumen fluid and feces. Furthermore, feeding the high-concentrate corn straw diet stimulated the mammary gland to release more pro-inflammatory cytokines. The results suggest that feeding a high-concentrate corn straw diet induce a higher pro-inflammatory response in the mammary gland and thus may partly decrease the milk production efficiencies in dairy cows.

Results

Concentrations of endotoxin in rumen fluid and feces of cows fed HCS were significantly higher than those of cows fed LCS and LCF. Feeding HCS increased the release of IL-1β, IL-6 and IL-8 in the mammary gland compared with feeding LCS. Concentrations of cytokines (IL-1β and IL-8) in mammary venous plasma had a negative correlation with milk production efficiencies. Conclusions: Results indicated that the high-concentrate corn straw diet increased the concentrations of endotoxin in rumen fluid and feces. Furthermore, feeding the high-concentrate corn straw diet stimulated the mammary gland to release more pro-inflammatory cytokines. The results suggest that feeding a high-concentrate corn straw diet induce a higher pro-inflammatory response in the mammary gland and thus may partly decrease the milk production efficiencies in dairy cows.

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