Retreatment with brentuximab vedotin for discordant peripheral T-cell lymphomas

使用维布妥昔单抗对不一致的外周T细胞淋巴瘤进行再治疗

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Abstract

Brentuximab vedotin (BV) has demonstrated efficacy against CD30(+) peripheral T-cell lymphoma (PTCL). We herein report a case of CD30(+) peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) that emerged one month after completing BV, cyclophosphamide, doxorubicin, and prednisone (BV-CHP) therapy for anaplastic large cell lymphoma (ALCL) and responded to retreatment with BV monotherapy. This case suggests that CD30(+) PTCL emerging shortly after BV-CHP therapy may respond to retreatment with BV monotherapy, even if the phenotype differs from the initial diagnosis.

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