Investigating Genetic and Environmental Substrates of the Relationship between Positive Mental Health and Biological Aging-A Study Protocol

研究积极心理健康与生物衰老之间关系的遗传和环境基础——一项研究方案

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作者:Francesca Marcon, Miriam Salemi, Cristina D'Ippolito, Angelo Picardi, Virgilia Toccaceli, Lorenza Nisticò, Sabrina Alviti, Ester Siniscalchi, Francesca Salani, Giorgia Maria Varalda, Emanuela Medda, Corrado Fagnani

Background

The Italian National Institute of Health (Istituto Superiore di Sanità) funded a 30-month project (July 2021-January 2024) to conduct a twin study of the relationships between Positive Mental Health (PMH) and cellular longevity. Only a few previous studies have focused on the biomarkers of aging in relation to psychological well-being, and none of them exploited the potential of the twin design. Method: In this project, following the standard procedures of the Italian Twin Registry (ITR), we

Conclusions

Biomarker assays are underway. Once data are available for the total study sample, statistical analyses will be performed. The project's results may shed light on new mechanisms underlying the mind-body connection and may prove helpful to promote psychological well-being in conjunction with biological functioning.

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