[Mortality predictive factors of a clinical cohort of elderly patients]

[老年患者临床队列的死亡率预测因素]

阅读:1

Abstract

OBJECTIVE: To study the association between the main variables collected in the comprehensive geriatric assessment (CGA) and mortality, in a clinical cohort of elderly people referred from primary care, following standardised criteria, to a geriatric unit. Design. Retrospective cohort study. SETTING: Outpatient department of a geriatric unit of a hospital in Madrid, Spain. PARTICIPANTS: A total of 140 patients older than 65 years were followed up for 70 months. MAIN MEASUREMENTS: We collected demographic, clinical, functional, and social variables during the CGA carried out by a multidisciplinary team. After 70 months we measured this cohort survival and we analysed the predictive factors for mortality using Cox hazard ratio analysis. RESULTS. Sixty three patients died after the 70 months of the study, and the survival median was 37 months. In the univariate analysis, age, male gender, diagnosed cancer, COPD, the Katz and Lawton indices, and the Mini-Mental State Examination (MMSE) score of 35 items, were significantly associated with mortality. In the multivariate analysis we found, as predictive factors for mortality: MMSE-35 (HR=0.965; 95% CI, 0.934-0.998; P=.037); male gender (HR=2.75; 95% CI, 1.6-4.74; P=.001); Katz score (HR=1.22; 95% CI, 1.04-1.43; P=.017); Lawton score (HR=0.93; 95% CI, 0.82-1.07; P=.30). CONCLUSION: Cognitive impairment is a mortality predictive factor (HR=0.65), for each point less in the MMSE-35, we observed an increase in mortality risk of 3.5% (1-HR) at 70 months, after adjustment for Katz and Lawton index and gender.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。