Parkinson's Disease: Diagnostic Challenges Amidst Transdiagnostic and Overlapping Mental Health Symptoms

帕金森病:跨诊断和重叠的精神健康症状带来的诊断挑战

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Abstract

Parkinson's disease (PD) is a complex neurodegenerative disorder with heterogeneous clinical presentations. Given the ambiguity of its overlapping symptomatology and concomitant atypical motor and neuropsychological symptoms its early diagnosis is clinically challenging. It is often missed since low mood, anhedonia, lack of motivation, and psychomotor retardation are commonly reported in individuals with PD. When alexithymia is the predominant symptom, the knowledge to discriminate between apathy, anhedonia, and alexithymia is critical to avoid misdiagnosis.

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