Abstract
NOMA, or oral labial necrosis, is a severe condition characterized by significant facial tissue destruction and elevated mortality rates, particularly in developing regions. Survivors often experience significant long-term consequences, leading to both functional and aesthetic impairments. The reconstruction of NOMA sequelae poses considerable challenges, including issues related to volume deficits, bone defects, and contracture deformities. This report presents two cases in which chimeric anterolateral thigh (ALT) flaps were effectively applied to address complex defects. The versatility of the ALT flap facilitated the reconstruction of multiple components, encompassing skin coverage, volume augmentation, and mucosal lining. This methodology offers a single-stage solution for reconstructing intricate NOMA sequelae, resulting in favorable functional and aesthetic outcomes.