Abstract
Herein, we report a 48-year-old male with lipofibromatous hamartoma-induced secondary carpal tunnel syndrome, treated successfully with decompression. The patient presented to the emergency with complaints of paresthesia and oedema of the wrists. When non-invasive methods failed to ease symptoms and nerve damage became a big concern, surgical intervention was recommended. Surgery to remove the nerve sheath and expose the carpal tunnel alleviated pressure on the median nerve. After a 3-year follow-up, the patient reported no discomfort, paresthesia, or limitation in wrist or finger movements, indicating a remarkable recovery. The tumour did not recur, and the sensorium was unharmed.