Hydrogen Sulfide as a Toxic Product in the Small-Large Intestine Axis and its Role in IBD Development

硫化氢作为小-大肠轴中的毒性产物及其在 IBD 发展中的作用

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作者:Ivan Kushkevych, Dani Dordević, Peter Kollar, Monika Vítězová, Lorenzo Drago

Conclusions

The optimum intestinal environment of D. piger Vib-7 can serve as a good indicator of the occurrence of inflammatory bowel diseases; meaning that these findings can be broadly used in medicine practice dealing with the monitoring and diagnosis of intestinal ailments.

Methods

Microbiological, biochemical, and biophysical methods, and statistical processing of the

Results

D. piger Vib-7 showed increased intensity of bacterial growth and hydrogen sulfide production under the following concentrations of sulfate and lactate: 17.4 mM and 35.6 mM, respectively. The study showed in what kind of intestinal environment D. piger Vib-7 grows at the highest level and produces the highest amount of hydrogen sulfide. Conclusions: The optimum intestinal environment of D. piger Vib-7 can serve as a good indicator of the occurrence of inflammatory bowel diseases; meaning that these findings can be broadly used in medicine practice dealing with the monitoring and diagnosis of intestinal ailments.

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