The novel bacteriocin romsacin from Staphylococcus haemolyticus inhibits Gram-positive WHO priority pathogens

溶血葡萄球菌产生的新型细菌素罗姆萨星可抑制革兰氏阳性菌 WHO 优先病原体

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作者:Runa Wolden, Kirill V Ovchinnikov, Hermoine J Venter, Thomas F Oftedal, Dzung B Diep, Jorunn Pauline Cavanagh

Abstract

Bacteria produce bacteriocins to inhibit growth of other bacterial species. We have studied the antimicrobial activity of a new bacteriocin produced by the skin bacterium S. haemolyticus. The bacteriocin is effective against several types of Gram-positive bacteria, including highly virulent and antibiotic-resistant strains such as Staphylococcus aureus and Enterococcus faecium. Effective antimicrobials are important for the treatment of infections and the success of major surgery and chemotherapy. Bacteriocins can be part of the solution to the global concern of antimicrobial resistance.

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