Nickel-catalyzed amination of aryl chlorides with ammonia or ammonium salts

镍催化芳基氯化物与氨或铵盐的胺化反应

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Abstract

The nickel-catalyzed amination of aryl chlorides to form primary arylamines occurs with ammonia or ammonium sulfate and a well-defined single-component nickel(0) precatalyst containing a Josiphos ligand and an η(2)-bound benzonitrile ligand. This system also catalyzes the coupling of aryl chlorides with gaseous amines in the form of their hydrochloride salts.

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