Development and validation of a nomogram for predicting early stress urinary incontinence following endoscopic enucleation of the prostate

建立和验证用于预测前列腺内镜剜除术后早期压力性尿失禁的列线图

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Abstract

PURPOSE: To develop and validate a predictive nomogram for early stress urinary incontinence (SUI) after endoscopic enucleation of the prostate (EEP) in patients with benign prostatic hyperplasia (BPH). METHODS: The records of 458 patients who underwent plasmakinetic- or diode-based EEP at our center from March 2016 to December 2019 were reviewed. Among these, 326 and 132 cases were randomly assigned to the training and validation set, respectively. A predictive nomogram was constructed based on multivariate logistic regression analysis. Receiver operating characteristic (ROC) analysis and calibration curves were employed to evaluate its performance. RESULTS: 65 years ≤ age < 70 years, 75 years ≤ age, 25 kg/m(2) ≤ BMI < 30 kg/m(2), 30 kg/m(2) ≤ BMI, 5 years ≤ LUTS duration, and 75 ml ≤ prostate volume were finally selected as independent predictors of early SUI into the multivariate logistics regression model. It was visualized as a concise nomogram with satisfactory discrimination and accuracy in both training and validation sets. CONCLUSIONS: A concise nomogram was developed and validated as a useful clinical tool for predicting early SUI post-EEP.

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