Abstract
PURPOSE: High rates of hearing loss are observed for individuals with Down syndrome, and regular hearing assessment is recommended for children and adults. Unknown variability of threshold estimates for repeated auditory assessments for individuals with diverse intellectual abilities, such as individuals with Down syndrome, confounds the ability to determine true threshold changes between assessments. This study evaluated variability of pure-tone thresholds measured within and across test sessions for individuals with Down syndrome. METHOD: Participants included 27 individuals with Down syndrome, ages 5.1-46.5 years (average = 22.7, SD = 11.8). A group of 11 neurotypical individuals, ages 15.9-48.6 years (average = 24.5, SD = 10.3) was included in intrasession variability assessment. Pure-tone thresholds in quiet were measured at 1, 4, 8, and 11.2 kHz during a single session or during repeated audiograms separated by 2.7-11.2 months (average = 5.8, SD = 2.4) and 3.0-3.9 years (average = 3.4, SD = 0.4). RESULTS: Intrasession variability was ≤ 10 dB for 94.3%-100% of thresholds for participants with Down syndrome, with similar variability observed for neurotypical participants. Threshold differences were ≤ 10 dB for 63.2%-85% of responses from audiograms separated by an average of 5.8 months and 37.5%-62.5% of responses separated by an average of 3.4 years. CONCLUSIONS: Intrasession variability for participants with Down syndrome aligns with current clinical standards accepting variability of ≤ 10 dB between repeated threshold estimates. Differences in repeated audiometric thresholds greater than 10 dB likely reflect true changes in hearing sensitivity. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.30052885.