Systemic inflammatory markers and sources of social support among older adults in the Memory Research Unit cohort

记忆研究组队列中老年人的全身炎症标志物和社会支持来源

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作者:Joanna McHugh Power, Sile Carney, Caoimhe Hannigan, Sabina Brennan, Hannah Wolfe, Marina Lynch, Frank Kee, Brian Lawlor

Abstract

Potential associations between systemic inflammation and social support received by a sample of 120 older adults were examined here. Inflammatory markers, cognitive function, social support and psychosocial wellbeing were evaluated. A structural equation modelling approach was used to analyse the data. The model was a good fit χ1082=256.13<math><mrow><msubsup><mi>χ</mi><mn>108</mn><mn>2</mn></msubsup><mo>=</mo><mn>256</mn><mo>.</mo><mn>13</mn></mrow></math> , p < 0.001; comparative fit index = 0.973; Tucker-Lewis Index = 0.962; root mean square error of approximation = 0.021; standardised root mean-square residual = 0.074). Chemokine levels were associated with increased age ( β = 0.276), receipt of less social support from friends ( β = -0.256) and body mass index ( β = -0.256). Results are discussed in relation to social signal transduction theory.

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