Abstract
This article contains the experimental and statistical data related to degradation of acetaminophen (paracetamol, APAP) by bacterial strains. The strains used in this study were isolated from wastewater by enrichment culture method. The optimization was important to identify the physical conditions at which the strain degraded the APAP effectively. Therefore, the Box-Behnken design (BBD) was used to know the influence of physical parameters (viz. pH, temperature, agitation speed, and concentration) on the degradation of APAP. The effects of the physical factor on the degradation process were investigated by a mathematical model, and this had indicated that all physical factors having some effect on the biodegradation of the APAP. Analysis of variance (ANOVA) showed that the strains DPP1, DPP3, DKP1, and DKP2 had the F-value of 12.89, 6.45, 4.58, and 5.31, respectively. This indicated, the model was significant with regression coefficient (R) value of 0.01%, 0.06%, 0.37%, and 0.18%, respectively. The experimental values, predicted data, and ANOVA analysis has suggested that the model was satisfactory.