Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity

肝脏连接蛋白 32 与非酒精性脂肪肝疾病严重程度相关

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作者:Jay Luther, Manish K Gala, Nynke Borren, Ricard Masia, Russell P Goodman, Ida Hatoum Moeller, Erik DiGiacomo, Alyssa Ehrlich, Andrew Warren, Martin L Yarmush, Ashwin Ananthakrishnan, Kathleen Corey, Lee M Kaplan, Sangeeta Bhatia, Raymond T Chung, Suraj J Patel

Conclusion

Hepatic expression of Cx32 strongly associates with steatohepatitis and fibrosis in patients with NAFLD. We also identify novel genes associated with NAFLD and suggest that Cx32 plays a role in promoting NAFLD development. (Hepatology Communications 2018;2:786-797).

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