Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

用于眼表成像的超高分辨率、长扫描深度全相位检测光学相干断层扫描技术

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Abstract

We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal-scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.

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