Ratiometric fluorescence nanoprobe based on nitrogen-doped carbon dots for Cu(2+) and Fe(3+) detection

基于氮掺杂碳点的比例荧光纳米探针用于检测Cu(2+)和Fe(3+)

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Abstract

Heavy metal ions pollution in environmental waters has an increasing impact on human health. As two common metal ions, copper ions (Cu(2+)) and ferric ions (Fe(3+)) widely exist in nature and play a vital role in life process. Therefore, it is significant to design sensitive and simple detection approaches for Cu(2+) and Fe(3+). In our work, the ratiometric fluorescence analysis method (denoted as N-CDs/OPD) was established for Cu(2+) and Fe(3+) detection. The N-CDs exhibited a Cu(2+) and Fe(3+) fluorescence quenching response properties. The o-phenylenediamine (OPD) may be oxidized to 2,3-diaminophenazine (DAP) by Cu(2+) and Fe(3+). With addition of Cu(2+) or Fe(3+), the fluorescence of N-CDs (436 nm) was quenched and a new peak at 556 nm (DAP) appeared, which realized fluorescent ratiometric detection of Cu(2+) and Fe(3+). The Cu(2+) concentration shows a good linear correlation versus fluorescence ratio (F(436)/F(556)) in the range of 10 to 30 µM (R(2) = 0.9981) with detection limit (LOD) of 0.86 µM. In addition, a good linear relationship between fluorescence ratio (F(436)/F(556)) and Fe(3+) concentration in the range of 20 to 80 µM (R(2) = 0.9880) with LOD of 7.12 µM. This nanoprobe realizes the detection of authentic samples successfully, which is expected to serve as a testing kit for analysis in water samples.

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