Abstract
Feedstock valorisation with preformed H(2)O(2) in conjunction with titanosilicate zeotypes is particularly attractive due to the increased selectivity, lower operating temperatures and improved process efficiency (particularly lower energy usage and enhanced atom economy) compared to aerobic pathways or alternative stoichiometric oxidants. However, numerous environmental and financial concerns associated with the application of commercial H(2)O(2) remain. These concerns have led to a growing interest in the application of the in-situ synthesized oxidant for a range of chemical transformations. Herein, we provide an overview of the key contributions to this emerging field of oxidative catalysis, with a particular focus on propene epoxidation and ketone ammoximation, which are currently two crucial industrial-scale processes that utilise preformed H(2)O(2) with the titanosilicate catalyst TS-1 for chemical synthesis. This contribution will highlight the potential for in-situ H(2)O(2)-mediated feedstock upgrading to replace existing technologies and contribute to the declared sustainability goals of the chemical synthesis sector.