Synthesis of furan-2-ones and spiro[furan-2,3'-indoline] derivatives using polyether sulfone sulfamic acid catalysis

利用聚醚砜氨基磺酸催化合成呋喃-2-酮和螺[呋喃-2,3'-吲哚啉]衍生物

阅读:2

Abstract

Polyether sulfone sulfamic acid (PES-NHSO(3)H) was prepared by simple sulfonation of a modified polyether sulfone. The number of acidic sites (SO(3)H) was determined to be 4.23 mmol H(+)/g by acid-base titration and 4.29 mmol H(+)/g by barium sulfate test. PES-NHSO(3)H was used as an efficient acidic catalytic system for the preparation of functionalized furan-2-ones and 2',5-dioxo-5 H-spiro[furan-2,3 ' -indoline]-3-carboxylate derivatives via the three-component reaction of anilines, aldehydes/1-ethylindoline-2,3-dione, and diethyl acetylene dicarboxylate in high yields (85-97%). The effect of polar and non-polar solvents on the productivity of the reaction was investigated. The catalyst was recovered 11 times without losses in catalytic potential.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。