Course of Illness and Treatment Updates for Bipolar Disorder in the Perinatal Period

围产期双相情感障碍的病程和治疗更新

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作者:Melissa M Batt, Aviva K Olsavsky, Shaleah Dardar, Celeste St John-Larkin, Rachel L Johnson, Mary D Sammel

Abstract

Purpose of review: The perinatal period is a time of increased vulnerability for people with bipolar disorder (BD). The purpose of this review is to provide an update of the literature from the last 3 years regarding course of illness and treatments for BD in the perinatal period to guide clinical care. Recent findings: Postpartum manic and depressive episodes are emerging as having a unique presentation that may differentiate them from non-perinatal mood episodes. Many important updates regarding medication treatment in the perinatal period have been published recently that have considered the risks of untreated illness versus treatment risks in this population.' Despite significant research, there are still gaps in knowledge regarding safety and efficacy of medications for the mother and child. Crucial future areas of study include improved screening guidelines, randomized controlled trials examining medication safety in pregnancy and lactation, and efficacy of nonpharmacologic treatments.

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