Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa

接触多种寄生虫与撒哈拉以南非洲地区活动性惊厥性癫痫的流行有关

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作者:Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia P Wilkins, John C Noh, Thomas B Nutman, Anthony K Ngugi, Rachael Odhiambo, Ryan G Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith H A Osier, Peter Odermatt, Charles R Newton; Study

Background

Epilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE), in five sites across sub-Saharan Africa.

Conclusion

This study investigates how the degree of exposure to parasites and multiple parasitic infections are associated with ACE and may explain conflicting results obtained when only seropositivity is considered. The findings from this study should be further validated.

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