Abstract
Portal vein thrombosis (PVT) is one of the most common serious complications in patients with liver cirrhosis. The occurrence of PVT not only aggravates the condition of liver cirrhosis but can also cause several serious complications, such as portal hypertension, esophagogastric variceal bleeding, and refractory ascites. All these factors have a serious impact on patients' quality of life and prognosis. This article evaluates the current evidence on the management of PVT in cirrhosis and explores the role of direct oral anticoagulants, but data on individualized anticoagulation strategies are limited and lacking for the treatment of PVT in cirrhosis, and it is hoped that it will inform a broad range of clinicians on the treatment of cirrhosis combined with PVT.