The nucleotide sequence of rat alpha-tubulin: 3'-end characteristics, and evolutionary conservation

大鼠α-微管蛋白的核苷酸序列:3'端特征及进化保守性

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Abstract

The structure and sequence of rat alpha-tubulin cDNA clone is being described. The 3'-end of the coding region contains the codon for a C-terminal tyrosine, which was previously considered to be post-translationally added to the completed polypeptide chain. A close homology in the coding sequence is observed when a-tubulin from rat and chick are compared, while the 3-non-translated region had diverged considerably.

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