Propensity matched analysis of DPA or DPL used within the first hour for severely hypotensive blunt trauma patients

对严重低血压钝性创伤患者在首小时内使用DPA或DPL进行倾向性匹配分析

阅读:1

Abstract

BACKGROUND: Prior single-center reports advocate for use of diagnostic peritoneal aspiration or lavage (DPA/DPL) to identify blunt trauma patients (BTPs) with intra-abdominal hemorrhage who require emergent surgery. Despite this, concerns exist over the potential for DPA/DPL to delay transfer to the operating room (OR). We hypothesized that DPA/DPL application in severely hypotensive BTPs would lead to increased OR transfer time and in-hospital mortality. METHODS: The 2017-2019 TQIP database was queried for adult BTPs presenting with severe hypotension (systolic blood pressure <70 mmHg) who underwent any operative intervention within two-hours. Using a 1:2 propensity-score model, patients who underwent DPA/DPL within one-hour of arrival were compared with those who did not, controlling for age, sex, comorbidities, ≥6 units of packed red cells within 4 h, and injury profile. RESULTS: From 5514 patients, 62 (1.1 %) underwent DPA/DPL. We matched 52 DPA/DPL patients to 104 patients not undergoing DPA/DPL. There were no differences in the matched variables between cohorts (all p > 0.05). Compared to those not undergoing DPA/DPL, patients undergoing DPA/DPL had a higher rate/risk of in-hospital complications (59.6 % vs. 39.4 %, p = 0.02) (OR 2.27, CI 1.15-4.47, p = 0.02) but statistically similar rate/risk of death (65.4 % vs. 50.0 %, p = 0.07) (OR 1.89, CI 0.95-3.76, p = 0.07). Time to OR was similar between both groups (DPA/DPL 39 min vs. non-DPA/DPL 42 min, p = 0.87). CONCLUSION: DPA or DPL used within the first hour of arrival does not appear to delay time to OR and does not increase risk of death. This challenges concerns over potential DPA/DPL-associated delays and heightened mortality risks.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。