Biomolecular Mechanisms and Case Series Study of Socket Preservation with Tooth Grafts

牙移植保留牙槽窝的生物分子机制及病例系列研究

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作者:Elio Minetti, Gianna Dipalma, Andrea Palermo, Assunta Patano, Alessio Danilo Inchingolo, Angelo Michele Inchingolo, Francesco Inchingolo

Conclusion

The study demonstrated positive bony healing in guided regenerative surgery procedures using autologous tooth grafts. However, further research with an extended follow-up period is necessary to thoroughly assess the potential of demineralized dentin autografts.

Methods

Twenty patients requiring tooth extraction underwent socket preservation utilizing the extracted tooth as the grafting material.

Results

After a 4-month healing period, the defects were significantly filled with newly formed hard tissue. Subsequently, bone biopsies were performed during dental implant placement to evaluate histological outcomes. The tissue exhibited a similar density to medium-density bone, displaying a homogeneous and uniform appearance without any visible signs of inflammation. The post-operative healing phase was free from infective complications or indications of graft particles within the regenerated bone structure. The histomorphometric analyses revealed the following results: bone total volume, BV% 52.6 ± 13.09, vital bone VB% 40.39 ± 15.86, residual graft % 12.20 ± 12.34.

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