Abstract
Humeral shaft nonunion is a challenging orthopedic condition that often requires surgical intervention for successful healing. In this case report, we present a 53-year-old male patient who presented with a humeral shaft nonunion, Underlying Systemic Disorders, and Arteriovenous fistula. The patient had a history of a previous humeral shaft fracture managed with open reduction and internal fixation but developed nonunion despite appropriate initial treatment. The complexity of this case was compounded by the patient's preference for a minimally invasive approach and the desire to avoid general anesthesia due to underlying medical conditions.