Clinical Profile, Etiology, and Outcomes of Patients With Eosinophilia: A Prospective Study From Western India

嗜酸性粒细胞增多症患者的临床特征、病因和预后:一项来自印度西部的前瞻性研究

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Abstract

This study investigated the clinical profile, etiology, and outcomes of eosinophilia in hospitalized patients. A total of 96 patients were included, with a mean eosinophil count of 3347.66 ± 1517.39 at admission, which decreased to 1265.39 ± 549.42 at discharge. The majority of patients were males. Common presenting symptoms included anorexia, abdominal pain, fever, fatigue, breathlessness, and cough. Idiopathic eosinophilia was the most frequent diagnosis, followed by parasitic infestations and atopy. Hypertension and ischemic heart disease were common co-morbid conditions. Elevated serum IgE levels were significantly associated with the severity of eosinophilia. Patients with severe eosinophilia had longer hospital stays and higher mortality rates, with no deaths observed in the mild eosinophilia group. The findings underscore the importance of thorough diagnostic evaluation, assessment of organ involvement, and management of associated co-morbidities.

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