Abstract
This study aimed to evaluate the effects of dietary nano-selenium (Se-NP), nano-zinc (Zn-NP), and their combination, on the performance of Ossimi ewes and their offspring. Twenty-eight pregnant Ossimi ewes were randomly allotted to one of four equal experimental groups. The ewes were fed a basal diet with the addition of 0.3 mg selenium nanoparticles (Se-NP), 30 mg zinc (Zn-NP), or 0.3 mg Se-NP plus 30 mg Zn-NP (SZ-NP)/kg DM. The results showed that nutrient digestibility, nutritive values, milk yield, and fat corrected milk, as well as milk constituents yields, were improved (p < 0.05) for ewes fed Se-NP, Zn-NP, or SZ-NP vs. the control one. As well, lambs' birth weight, final body weight, and average daily gain were increased (p < 0.05). Serum immunoglobulin G, total protein, albumin, globulin, and glucose values were higher (p < 0.05); however, serum cholesterol level tended to be decreased. Ewes and their respective lambs in the Se-NP, Zn-NP, or SZ-NP groups had lower (p < 0.05) urea concentrations and liver enzyme activity than the control. Thyroid hormones, total antioxidant capacity, and glutathione peroxidase activity were higher (p < 0.05) in the Se-NP-, Zn-NP-, or SZ-NP-fed groups. This improvement was accompanied by favored growth performance, immune function, and overall health in their suckling lambs, with selenium being more effective than zinc. In conclusion, the dietary inclusion of selenium, zinc nanoparticles, or their combination can be an effective strategy to enhance productivity and health in ewes and their offspring.