Abstract
BACKGROUND: Atraumatic brain injury and traumatic brain injury (TBI) have been demonstrated to be associated with changes in brain electromagnetic field (EMF) activity due to alterations in the structure and function of neural circuitry. Modulation of abnormal EMF activity through EMF stimulation may promote neural regeneration and may be more beneficial when the specific change in EMF frequency that is correlated with either computed tomography (CT) imaging changes, neurological changes, or both can be precisely localized. The authors investigate the efficacy and feasibility of a noninvasive portable helmet with sensors and built-in signal generators to measure and localize specific changes with frequency and amplitude from brain EMF for both atraumatic and TBI patients. METHODS: This prospective clinical study was conducted from January 2025 to February 2025 and enrolled patients greater than 18 years old diagnosed with atraumatic and TBI, including negative image concussion. Baseline EMF activity was recorded using a helmet equipped with 20 sensor stimulators. Localization of EMF activity was determined based on sensor activity corresponding to the patient's neurological deficits on exam and/or structural lesion(s) on CT. EMF data were collected using the DAQami software (Dataq Instruments, Akron, OH) and analyzed using fast Fourier transformation with the Igor Pro 8 software (Wavemetrics Inc., Lake Oswego, OR) to localize normal and abnormal brain EMF signals by comparing opposing and adjacent sensors. RESULTS: Ten patients were enrolled in this study with a mean age of 47.1 years. Mechanisms of injury included spontaneous hypertensive intracranial hemorrhage (one patient) and head trauma after motor vehicle collision (auto vs. auto; auto vs. motorcycle; and auto vs. pedestrian), dirt bike accident, and ground-level fall (nine patients). Radiographic findings included spontaneous basal ganglia hemorrhage (one patient), isolated traumatic subdural hematoma (one patient), traumatic subarachnoid hemorrhage (one patient), and no intracranial abnormalities (seven patients). Abnormal EMF activity was recorded and correlated with neurological deficits on exam, CT findings, or both, demonstrating the usefulness of EMF in localizing brain injuries. CONCLUSIONS: These results demonstrate the efficacy and feasibility of utilizing a noninvasive portable helmet for real-time EMF recording and localization of brain abnormalities in atraumatic and TBI patients, including image-negative concussions. EMF measurements may aid in monitoring recovery after atraumatic brain injury and TBI and enable the clinician to tailor treatment plans based on the patient's unique brain EMF patterns.