Abstract
INTRODUCTION: The aim of this study was to evaluate the postoperative pain in patients using 8.25 % sodium hypochlorite compared to 5.25 % Sodium Hypochlorite concentration without activation and using sonic and ultrasonic activation methods after single visit root canal treatment. METHODS: In this double blind randomized trial, a total of 120 participants mandibular premolar with symptomatic irreversible pulpitis were included and randomly divided into 6 groups based on the different concentration of sodium hypochlorite and activation methods (sonic & ultrasonic activation) i.e. Group 1: 5.25 % NaOCl with no activation method, Group 2: 8.25 % NaOCl with no activation method, Group 3: 5.25 % NaOCl with sonic activation, Group 4: 5.25 % NaOCl with Ultrasonic activation, Group 5: 8.25 % NaOCl with sonic activation, Group 6: 8.25 % NaOCl with ultrasonic activation. The presence of postoperative pain was assessed 24, 48, and 72 h after treatment and recorded using the visual analogue scale (VAS). RESULTS: Intragroup postoperative pain in all six groups reduced after 24 h, 48 h and 72 h, showing statistically significant differences. At all-time intervals, postoperative pain was higher in the groups that used ultrasonic stimulation. CONCLUSION: At all-time intervals, there was no significant difference in the presence of postoperative pain between the 8.25 % NaOCl and 5.25 % NaOCl irrigation solutions with no activation method and sonic activation compared to ultrasonic activation.