Renal transplantation in patients with Alport syndrome: patient selection, outcomes, and donor evaluation

Alport综合征患者的肾移植:患者选择、预后和供体评估

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Abstract

Alport syndrome is an inherited disorder of basement membrane collagen IV that frequently results in end-stage renal disease. Patients with Alport syndrome who undergo renal transplantation have generally excellent outcomes. Posttransplant antiglomerular basement membrane nephritis is a rare complication of renal transplantation for Alport syndrome. Because Alport syndrome is a genetic disorder, potential related donors must be carefully evaluated in order to minimize harm.

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