Solitary nodule of angiolymphoid hyperplasia with eosinophilia of the back masquerading as pyogenic granuloma

背部孤立性血管淋巴样增生结节伴嗜酸性粒细胞增多,易误诊为化脓性肉芽肿

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Abstract

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare chronic inflammatory disorder of unknown etiology that most commonly presents as painless lymphadenopathy or subcutaneous masses in the head and neck region. The pathogenesis of the disease is not yet clear. The differential diagnosis is determined using characteristic histological features, such as significant vascular proliferation, lymphocytes and eosinophil inflammation in the dermis. Here is presented the case of a patient with a solitary nodule of ALHE masquerading as pyogenic granuloma (PG). A 47 year-old male patient was admitted with an isolated lump on the right side of the back, which had been present for ~6 months; the nodule appeared to have characteristics of PG and was ~1.8×1.0 cm(2) in diameter. To the best of our knowledge, this is the first case report regarding ALHE arising in the back. The present report discusses the manifestation, histopathological features and treatment of the case.

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