Abstract
RATIONALE: Angiomyolipoma is a benign mesenchymal tumor that consists of adipose tissue, muscle cells and blood vessel. Renal angiomyolipomas represent almost one percent of all renal tumors. PATIENT CONCERNS: We reported a case of a 42-year-old woman complaining of mild abdominal pain with no other symptoms and no remarkable medical history. DIAGNOSIS: Clinical examination was inconclusive and revealed a large, smooth, non-tender, and immovable mass in the right abdomen. Ultrasound examination confirmed the existence of a large, homogeneous, hyperechoic tissue mass. Abdominal multi-slice computed tomography (CT) scans also confirmed the presence of a well-rounded mass in the right abdomen. The histopathology tests confirmed the diagnosis of a large retroperitoneal mass. INTERVENTIONS: The patient underwent a traditional laparotomy without complications to remove the tumor. OUTCOMES: The open surgery was the best option, and the patient's condition improved due to the following-up. LESSONS: Retroperitoneal extra-renal angiomyolipomas are extremely rare, and in this case, we document a case of retroperitoneal angiomyolipoma manifested with only mild abdominal pain in Syrian women.