Autonomic nervous system dysfunction in workers exposed to organic solvents

Tests for cardiovascular function were made in 34 workers exposed to organic solvents for several years (mean 16.2 years). The results were compared with those of 52 healthy subjects. All the cardiovascular parameters were lower in the exposed group. The exposed subjects with evidence of peripheral neuropathy had lower values than those without neuropathy. The findings suggest that peripheral parasympathetic nerves may also be involved in mild sensory-motor peripheral neuropathy among subjects with long-term occupational exposure to organic solvents.