Effects of bolus tube feeding on cerebral blood flow velocity in neonates

推注式管饲对新生儿脑血流速度的影响

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Abstract

AIM: To study continuously cerebral blood flow velocity in the middle cerebral artery before, during, and after tube feeding in neonates. METHOD: Cerebral blood flow velocity was measured in 14 neonates using a Doppler ultrasound device. Blood pressure, respiration, and oxygen saturation were monitored. RESULTS: Mean blood flow velocity decreased from 37 cm/s before feeding to 33 cm/s (P < 0.001) 5 to 11 minutes after feeding. Prefeeding values were reached after 17 minutes. Arterial blood pressure, respiration patterns, and oxygen saturation did not change significantly during the study period. CONCLUSION: Tube feeding in preterm infants may decrease cerebral perfusion, despite unchanged blood pressure and unchanged oxygen saturation.

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