Toward equitable biomarkers of aging: rethinking methylation clocks

迈向公平的衰老生物标志物:重新思考甲基化时钟

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Abstract

DNA methylation clocks, which measure biological age by analyzing age-related DNA methylation patterns, offer powerful biomarkers of aging. But as a recent preprint highlights, current models underperform in diverse populations. The next generation of clocks must prioritize equity to avoid reinforcing disparities in precision aging and disease risk prediction.

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