Heme-nitrosylated hemoglobin and oxidative stress in women consuming combined contraceptives. Clinical application of the EPR spectroscopy

服用复方避孕药的女性的血红素亚硝化血红蛋白和氧化应激。EPR 波谱的临床应用

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作者:Irina I Lobysheva, Sandrine van Eeckhoudt, Flavia Dei Zotti, Ahmad Rifahi, Lucie Pothen, Christophe Beauloye, Jean-Luc Balligand

Conclusion

This cross-sectional cohort study demonstrates that a decrease of HbNO measured by quantitative EPR in human venous erythrocytes is correlated with the development of endothelial dysfunction under CPs consumption, in parallel with increased vascular oxidative stress.

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