[Growth of Children with Neonatal Short Bowel Syndrome: Its Relationship to Gestational Age]

[新生儿短肠综合征患儿的生长发育:与胎龄的关系]

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Abstract

INTRODUCTION: It has been described that children with chronic intestinal failure secondary to short bowel syndrome have an impact on growth. OBJECTIVE: To compare the growth of children with chronic intestinal failure secondary to neonatal short bowel syndrome between newborns of gestational age ≥ 36 weeks and 6 days Group 1 and < 36 weeks Group 2, evaluated at two years of age and during childhood. METHODS: Longitudinal, retrospective, analytical study of children with neonatal short bowel syndrome and chronic intestinal failure. Growth, weight/age z-score, height/age z-score and body mass index/age z-score (World Health Organization) were determined at 2 years of age; a posteriori, we analyzed the beginning and end of a period of one year between 2-9 years of age of the same patients. RESULTS: Group 1: 13 patients, Group 2: 8 patients. A greater impact on height/age z-score was found in Group 2 at 2 years (p < 0.008). During the analyzed period after 2 years, it was observed that the weight/age z-score and the body mass index z-score/age remained stable, while the height/ age z-score worsened in both groups. CONCLUSION: Children with < 36-weeks of gestational age had a greater impact on longitudinal growth at 2 years and both groups studied had a negative impact on height growth after 2 years.

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