Transient unilateral oculomotor and trigeminal nerve palsy following intranasal local anesthetic infiltration: a case report

鼻内局部麻醉浸润后出现短暂性单侧动眼神经和三叉神经麻痹:病例报告

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Abstract

BACKGROUND: Complications from in-office inferior turbinate (IT) and septal swell body coblation typically include pain, congestion, and bleeding. However, rare cases of cranial nerve palsies from local anesthetic infiltration can occur. We present a rare case of an oculomotor nerve palsy and palsies of the ophthalmic (V1) and maxillary (V2) branches of the trigeminal nerve following intranasal local anesthetic infiltration prior to coblation, a complication not previously documented in the literature. Awareness of such rare and transient complications can help surgeons and clinicians avoid unnecessary interventions and better counsel patients. CASE DESCRIPTION: A 75-year-old female with a one-year history of recalcitrant bilateral nasal obstruction underwent an in-office primary bilateral coblation of the ITs and septal swell bodies. Four percent lidocaine-soaked neuropatties were applied over the ITs and septal swell bodies, followed by infiltration with 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine. Shortly after infiltration, the patient developed left-sided ptosis and was unable to adduct the left eye, causing diplopia. Additionally, the patient reported paresthesia in the V1 and V2 dermatomes. All symptoms resolved within 15 minutes. At the 6-week post-procedure visit, there was no sustained diplopia, left eye ptosis, or facial paresthesia. These symptoms also remained absent at the six-month post-procedure visit. CONCLUSIONS: Although relatively low-risk, surgeons should be aware of potential cranial nerve complications associated with intranasal anesthetic administration. Recognizing the benign and reversible nature of such presentations may help avoid unnecessary diagnostic workups, reduce patient distress, and reinforce best practices such as aspiration prior to infiltration and slow injection techniques.

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