Abstract
BACKGROUND: Patients with clonal cytopenia of undetermined significance (CCUS) who undergo hip replacement surgery are at risk of serious complications such as bleeding, infection, and anemia. There are certain difficulties in clinical treatment. Such cases have not been reported in international medical journals. CASE DESCRIPTION: A 35-year-old man with CCUS for 4 years developed bilateral avascular necrosis of the femoral head 1 year after hormone therapy for the blood disorder. The patient required arthroplasty surgery due to hip pain and functional limitations. The patient's persistent severe deficiency of platelets, red blood cells, and granulocytes limited the operation. Before surgery, the multidisciplinary team formulated the blood transfusion treatment plan for correcting blood system abnormalities, the treatment plan for basic internal medicine diseases, the minimally invasive manipulation anesthesia plan, the surgical plan, the postoperative refined care and the rapid recovery plan. We completed bilateral hip arthroplasty surgery for patients and had good recovery of hip joint function during the 6-month follow-up after surgery (Harris Hip Score =90 points). CONCLUSIONS: CCUS patients have a higher operation risk when perform the total hip arthroplasty. Under the collaborative treatment of the multidisciplinary team, we successfully completed the patient's surgery and achieved a good surgical outcome.