Piezo1 channels are mechanosensors in human fetoplacental endothelial cells
Piezo1 通道是人类胎儿胎盘内皮细胞中的机械传感器
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作者：L C Morley, J Shi, H J Gaunt, A J Hyman, P J Webster, C Williams, K Forbes, J J Walker, N A B Simpson, D J Beech
| 期刊： | Molecular Human Reproduction | 影响因子： | 3.600 |
| 时间： | 2018 | 起止号： | 2018 Oct 1;24(10):510-520. |
| doi： | 10.1093/molehr/gay033 | 方法学： | Cell Culture |
| 靶点： | Endothelial cell medium | 研究方向： | 免疫、细胞生物学 |
| 细胞类型： | 内皮细胞 | |
Methods
We investigated the relevance of Piezo1 to placental vasculature by studying human fetoplacental endothelial cells (FpECs) from healthy pregnancies. Endothelial cells were isolated from placental cotyledons and cultured, for the study of tube formation and cell alignment to shear stress. In addition, human placental arterial endothelial cells were isolated and studied immediately by patch-clamp electrophysiology. Main
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