Abstract
We evaluated whether non-invasive estimated inspiratory muscle pressure (P(mus)) predicts extubation outcomes in ICU patients. Estimated P(mus), reflecting the pressure generated by respiratory muscles, was measured before and after the spontaneous breathing trial (SBT). Lower pre-SBT estimated P(mus) (<4.1 cmH₂O) and post-SBT (<4.4 cmH₂O) were associated with extubation failure (AUC ≈ 0.73). P0.1 and dynamic transpulmonary pressure (P(L,dyn)) showed no significant association. Estimated P(mus) offers a simple bedside method to assess inspiratory muscle strength and may help identify patients at risk of extubation failure. Further multicenter studies are needed to validate these findings.