Abstract
This retrospective observational analysis was conducted to explore the correlation between the frequency of bleeding in digestive system tumors and various coagulation indexes, providing clinical data for predicting multiple bleeding episodes in patients. A retrospective collection was made of 41 patients with digestive system tumors who presented with gastrointestinal bleeding in our hospital from 2020 to 2024. The number of bleeding episodes ranged from 1 to 5. At the same time, the coagulation indexes at the time of admission were collected. The SPSS statistical software was used to analyze the correlation between the number of bleeding episodes and the coagulation indexes. A positive correlation was found between the number of bleeding episodes and the percentage activity of prothrombin (Pearson r = 0.199, p = 0.034), while there was no significant correlation with other coagulation indexes (prothrombin time, international normalized ratio, partial thromboplastin time, thrombin time, fibrinogen, and D - dimer). Also, no significant correlation was found between the number of bleeding episodes and other clinicopathological characteristics of the patients. The continuous increase in the elevated percentage activity of prothrombin may be associated with predicting re-bleeding in patients with digestive tract tumors.