Abstract
Tuberculous pericarditis is often difficult to diagnose because of atypical symptoms and insufficient etiology examination. We present a case wherein the patient initially presented with a high fever accompanied by recurrent pericardial effusion. Notably, the etiology and genetic diagnosis of tuberculosis were negative. With the combined application of multimodal imaging techniques such as transthoracic echocardiography, transesophageal echocardiography, contrast-enhanced ultrasound and enhanced CT, clinical diagnosis and treatment can provide sufficient evidence to support tuberculous pericarditis. Following the definitive diagnosis, the patient received an adequate course of antituberculosis treatment, and the condition improved significantly, with no recurrence of symptoms.