Sodium Valproate-Induced Gingival Enlargement in a Pediatric Patient: A Case Report With Surgical Intervention

儿童患者因服用丙戊酸钠引起的牙龈增生:一例手术治疗病例报告

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Abstract

Gingival enlargement occurs secondary to the usage of anti-epileptics. The severity of overgrowth varies among different classes of drugs, with phenytoin having the highest incidence of reported cases, whereas cases associated with sodium valproate are minimal. Factors like drug dose, genetic factors, plaque, gingival inflammation, and periodontal health influence the degree of overgrowth. This case report presents one of the first surgically managed cases of generalized gingival enlargement in a pediatric patient due to chronic usage of sodium valproate.

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