The Role of JAK Inhibitors in Pediatric Lichen Sclerosus et Atrophicus: A Case Report

JAK抑制剂在儿童硬化性萎缩性苔藓中的作用:病例报告

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Abstract

Lichen sclerosus (LS) is an uncommon mucocutaneous condition that primarily affects the genitoanal region and is characterized by white, porcelain-like sclerotic lesions. Although its incidence peaks after menopause, LS can also occur in children, affecting both the genital and extragenital areas. We present the case of a pediatric patient with both genital and extragenital LS who responded well to oral tofacitinib therapy. This case highlights that oral tofacitinib is a safe and effective treatment option for lichen sclerosus et atrophicus (LSA) in the pediatric population.

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