Single-Unit Comonomer Insertion Initiates Radical Polymerization of Thionolactone to Give Chemically and Thermally Degradable Polythioesters

单单元共聚单体插入引发硫代内酯的自由基聚合,生成化学和热可降解的聚硫酯

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Abstract

Polythioesters are promising as sustainable materials with improved properties. But, despite the industrial importance of radical polymerization, polythioester homopolymers are not readily accessible through this method. Using dibenzo-[c,e]-oxepin-5-(7H)-thione (DOT) as a thionolactone monomer, this study shows that the attempted radical homopolymerization suffers from low (3-13%) conversion. Conversely, addition of diethyl vinylphosphonate (DEVP), a judiciously chosen comonomer, led to near-quantitative DOT conversion at low (<22%) DEVP incorporation. Thorough analysis of the products by (1)H-(1)H COSY, (1)H-(13)C HMBC, and (1)H-(31)P HMBC NMR spectroscopy revealed that DEVP was inserted as single units and enabled the identification of DEVP repeat units sandwiched between two DOT groups (δ(P) = 24.5 ppm) and those located at the α end group between an AIBN-derived fragment and a DOT repeat unit (δ(P) = 23.7 ppm). The proportion of single DEVP repeat units at the α end group increased with a decreasing DEVP copolymerization feed, demonstrating the importance of the secondary DEVP-based radical in effectively initiating the polymerization of DOT. Polymers that carried, on average, less than one internal DEVP unit and consisted mostly of AIBN-DEVP-initiated DOT homopolymers were prepared by tuning the DEVP feed ratio. The polymers were fully degradable through aminolysis and by heating (in bulk) to 140 °C, with a higher DEVP content found to increase the formation of dibenzo-[c,e]-thiepin-5-(7H)-one (DTO) thiolactone product during thermal degradation.

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