Abstract
Guillain-Barré Syndrome (GBS) is a rare, immune-mediated polyneuropathy that typically presents with ascending weakness, areflexia, and sensory disturbances. This case highlights an atypical presentation of GBS in an 18-year-old female, whose initial symptoms included primarily sensory deficits following routine exercise. The diagnostic process was complicated by unremarkable initial laboratory and imaging findings, but cerebrospinal fluid analysis revealed albuminocytologic dissociation, and electromyography confirmed acute demyelinating polyneuropathy. This case underscores the diagnostic challenges posed by atypical variants of GBS, the importance of thorough neurological evaluation, and the critical role of timely intervention in optimizing outcomes.