Abstract
Desquamative gingivitis (DG) is important in oral medicine because it is not a pathologic entity itself; rather, it is a clinical manifestation of dermatological disease most frequently associated with chronic inflammatory (e.g., oral lichen planus) and autoimmune diseases, mainly pemphigus vulgaris and mucous membrane pemphigoid, and several cases have been reported till date. Herein, we describe a case of pemphigus vulgaris-associated DG with unusual clinical behavior, in which the gingival lesions spontaneously resolved after consistently showing no response to various treatments. Additionally, a brief review of the literature focusing on the management of DG is provided.