Abstract
Published literature about patients with polycythemia vera (PV) undergoing cardiac surgery while utilizing cardiopulmonary bypass (CPB) is scarce, even more so when coupled with an additional rare bleeding disorder. These patients require a multidisciplinary approach to achieve optimal clinical management. Several cases have been reported of oxygenator failure or thrombosis within the extracorporeal circuit. We present a successful CPB run on a patient with coexisting PV and Factor X deficiency undergoing coronary artery bypass grafting.